Endocrine Abstracts

Objectives: To describe the results of the bilateral inferior petrosal sinus sampling (BIPSS) performed in our hospital for differential diagnosis between Cushing disease (CD) and ectopic ACTH secretion (EAS), and evaluate if CRH stimulation during this test improves its diagnostic accuracy.Material and Methods: We retrospectively review 29 BIPSS performed in 26 patients (4 men, 22 women), with mean age of 44.7 year-old (range 28–69), diagnosed wit...

Surgical factors, in particular a higher volume of operations and a dedicated neurosurgeon, are considered the main determinants of surgical complication rates in transsphenoidal surgery (TSS). We evaluated postoperative complications in a large series of TSS for non-producing adenomas included in TESSPAIN, a retrospective multicenter nationwide registry. All TSS performed at the 29 participating centers between 2018 and 2022 were included. Globally, 1421 non-producing pituita...

Transsphenoidal surgery (TSS) of the hypothalamic-pituitary region is the approach of choice because of its lower morbidity compared to the transcranial approach. However, its results are highly variable and depend on many factors related to the tumor itself, to the medical team, and to technical issues. We review the situation of this procedure in a nationwide retrospective multicenter evaluation. Data were collected from centers participating in the TESSPAIN (TranssphEnoidal...